Cardiovascular Injury, Repair & Regeneration

The Cardiovascular Injury, Repair & Regeneration theme comprises a collaboration of clinical and basic scientists.  Current areas of research focus are:

  1. Pathways to vascular regeneration
  2. Calcification and fibrosis in repair and remodelling
  3. Clinical Translation

Metabolism, Obesity, and Diabetes

Lipid droplets in zebrafish

The Metabolism Obesity and Diabetes Theme at the Centre for Cardiovascular Sciences, QMRI brings together clinical and basic scientists with an interest in the physiology and pathophysiology of metabolic processes relevant to obesity, diabetes and cardiovascular disease. Our research covers developmental processes (e.g. in utero effects), genetics and epigenetics, mature cell function and pathogenesis (e.g. Inflammation), through to regeneration and transplant of organs that are central to metabolic homeostasis: adipose (visceral, marrow, brown), liver, heart, kidney, pancreatic islets and lymphoid tissue. The aim of the Metabolism Obesity and Diabetes Theme is to act as a forum for cross-disciplinary collaborations aimed at understanding and ultimately treating cardiometabolic diseases.

Cardio-metabolic Imaging

Non-invasive imaging techniques have revolutionised the ability to determine primary causes of cardiac, vascular and metabolic disease as well as the efficacy of potential therapies. The Cardio-metabolic Imaging theme is a PI lead group of physicists, engineers, clinicians and biologists who work together, as well as across CVS themes and external collaborations, to generate disease modelling and novel imaging techniques that will ultimately improve diagnosis and future therapies.

Hypertension & Renal

High blood pressure is the major risk factor driving the global crisis of non-communicable disease, chiefly Cardiovascular Disease and Chronic Kidney Disease. These diseases reduce the quality of life for millions of people and the medical care is costly. Cardiovascular disease is the leading cause of death worldwide: patients with kidney disease are more likely to die of a cardiovascular complication than progress to renal failure. The Hypertension and Renal theme focusses research on these global health challenges.