The University/BHF Centre for Cardiovascular Science (CVS) is a multidisciplinary research centre co-located with the Royal Infirmary of Edinburgh - a large teaching and research hospital and major clinical trials hub, the Edinburgh Medical School and the University of Edinburgh’s biomedical research facilities, providing a collaborative, cross-disciplinary working environment for academia, industry and clinicians.
Cardiovascular disease is a major health problem, encapsulating a range of conditions including myocardial infarction, coronary heart disease, arterial thrombosis, peripheral artery disease, stroke and angina. A major underlying cause of cardiovascular disease is artherosclerosis and subsequent tissue ischaemia, which may be associated with conditions such as obesity, diabetes, kidney disease, hypertension and high cholesterol. Research in the CVS is investigator-led, but there are focal disease themes which span from the origins and risk factors for the development of disease to the factors which determine tissue recovery from ischaemia. Research groups associated with CVS are world-leading in a number of underlying processes, ranging from early life development to neuroendocrine and steroid signalling to tissue regeneration. The technologies employed within CVS span basic molecular and cell biology, to model organisms (flies, fish, rodents), to clinical trials.
The ethos in the CVS is that, whatever their background, investigators can use this network of collaboration and training to deliver fundamental discoveries and implement them in translational research.