Metabolic Disease

Metabolic Disease

Image of atherosclerotic lesions

Obesity is a major health problem with approximately one in five people classed as obese and a further quarter of us classed as overweight. Obesity substantially increases the risk of developing metabolic diseases such as type two diabetes and high cholesterol and substantially increases the risk of having a heart attack or stroke (cardiovascular disease). At present, there are very few treatments for obesity and it is not fully understood how obesity causes metabolic disease.

In the Centre for Cardiovascular Science we use a range of approaches to study obesity and metabolic disease. Our research spans areas such as identifying which genes make us more likely to gain weight, determining which processes go wrong in obesity and how these cause metabolic disease, to finding new treatments for obesity and diabetes to improve metabolic health.